Reviews are from verified customers who purchased the product on SupplementRelief.com. They are intended to describe the quality and usefulness of the specific product i.e. "how is the product working for you?".
on August 9, 2023 - Verified Purchase
I have been using Tranquinox Deep for a couple of months now. This sleep aide has worked for me, and I have had sleep issues for many years.
on June 21, 2023 - Verified Purchase
it is what cure my imsomnia on 10 months
Satisfied and happy
on June 12, 2023 - Verified Purchase
I used to sleep only 4-5 hours daily and with this product so far I am up to 7 hours.
I know I will fall asleep
on April 9, 2023 - Verified Purchase
on April 10, 2021 - Verified Purchase
Helps most night in getting me to fall asleep and stay asleep .
on March 22, 2021 - Verified Purchase
was skeptical but the friend that recommended it said just try it. It really works I go to sleep and sleep all night with no drug hangover!!!
on March 8, 2021 - Verified Purchase
This is a great product! It is our product of choice for sleepless nights.
on January 17, 2021 - Verified Purchase
It helps keep me asleep as long as I need to be without frequent interrupts
on November 20, 2020 - Verified Purchase
A safe sleep aid that actually works!
Mrs. Terri Pearsons
on November 5, 2020 - Verified Purchase
Works fast. Though I don't always sleep through the night taking Tranquinox makes it happen more often.
on July 23, 2020 - Verified Purchase
Helps with sleep and anxiety
on May 15, 2020 - Verified Purchase
I have anxiety and depression since 2012 and Tranquinox is like magic! I take 6 sprays when I get into bed and i can't keep my eyes open after about 20 mins. or so AND I only wake up once instead of 3 times AND I go right back to sleep. I mean it's been a miracle for me!
on April 22, 2020 - Verified Purchase
I just started taking the supplements so it's too soon to notice a difference. No difference and lack of sleep the first three nights of taking this product
on April 9, 2020 - Verified Purchase
Works well and no grogginess
on March 27, 2020 - Verified Purchase
My doctor recommended this product for my anxiety and difficulty sleeping. It has been working well and I will continue to take this product as it is a natural alternative to medication.
on March 18, 2020 - Verified Purchase
Only use about 1/2 the recommended dosage, but within 30 minutes I'm falling asleep and stay asleep for hours - yet wake up without that drowsy feeling from prescription sleep-aids.
on February 2, 2020 - Verified Purchase
I sleep like a baby on this product. Have no trouble falling asleep and i stay asleep each night for full eight hours of sleep. Highly recommend!
on November 10, 2019 - Verified Purchase
I am so grateful for this product. It has brought peaceful, non-drugged sleep.
In Need of REST?
on September 9, 2019 - Verified Purchase
I have been struggling with insomnia - Tranquinox has helped me without side effects. There are many products out for sleep, but they are dangerous; you may not know the harm they are doing. I am resting now and not worrying! Thank you NuMedica!
Many people have problems getting to sleep and staying asleep for long enough during the night. Healthcare professionals recommend 8 hours of sleep as optimal in order to avoid experiencing a variety of symptoms that include fatigue, confusion, irritability, depression, malaise, and headaches. It is important to identify the causes of sleep issues as lack of sleep can sometimes be due to medical problems such as sleep apnea - a disorder that causes a person to stop breathing for short periods of time during the night. Fortunately, a number of lifestyle changes combined with natural products are available to help people get a good night's sleep.
Liposomal Tranquinox has a blend of powerful rest and relaxation ingredients that offers a natural alternative for promoting healthy sleep patterns, supporting relaxation, and calming anxiety. The formula contains a blend of powerful ingredients like GABA, melatonin, and glutathione to stabilize normal circadian rhythms and promote restful sleep. This proprietary formula is delivered in a non-GMP phosphatidylcholine liposome complex for optimal absorption and bioavailability.
Melatonin is a primary hormone that is naturally produced by the pineal gland. It has been found that melatonin is intimately involved in setting the body's internal clock in the brain, generating normal circadian rhythms, and synchronizing hormone secretions. Scientific evidence has shown that melatonin is closely associated with the function of our circadian, neurological, and immune systems. It is a powerful Chrono biotic that helps support the normal sleep-wake cycle during 'biological night' time. It has been found that melatonin levels are at a peak during ''biological night' time. Preliminary findings suggest that melatonin may help promote restorative sleep and support normal nerve function.*
GABA (Gamma Aminobutyric Acid) is an amino acid neurotransmitter that is involved in carrying information between the nerve cells of the body. It is critical for the healthy function of the nervous system and is well-known to have a calming effect on the body.*
Glutathione, an important antioxidant support nutrient that plays an important role in the detoxification of body systems.*
How does it Work?
There appear to be two probable interacting effects that melatonin can have on the sleep/wake cycle:
entraining and shifting the circadian rhythm in a 'Chrono biotic' function;
promoting sleep onset and continuity of sleep in a 'hypnotic' function by promoting the homeostatic 'drive' to sleep.
These two effects appear to be equal and melatonin taken in the evening can enhance both these phases. The use of timed melatonin dosages can have varying degrees of effectiveness in circadian rhythm sleep disorders. As a rule, lower doses are better for delayed sleep phase syndrome while higher doses are indicated for sleep disorders due to shift work or jet lag.
It is generally accepted that melatonin has a remarkably benign safety profile when treated with pharmacological doses. The potent ingredients combined with liposomal technology in Liposomal Tranquinox can promote the restful, relaxed state the body needs for natural sleep cycles. The specialized blend of melatonin, GABA, and glutathione provides relief from occasional sleeplessness by supporting and enhancing healthy melatonin function and optimizing the body's natural sleep mechanism.
About Liposomal Technology
Liposomes (a carrier molecule) are actively transported. A liposome is a phospholipid (important molecules that provide structure and protection to cells) that forms a barrier around its contents. This barrier is resistant to enzymes in the mouth and stomach, alkaline solutions, digestive juices, bile salts, and intestinal flora that are generated in the human body, as well as free radicals. Liposomes pass through the digestive process much like the Trojan Horse passed through the city gates of Troy. Inside of the liposome is the target nutrients of the supplement much like the Greek soldiers were hidden inside of the horse. The liposome stays in tact until it passes through the small intestine wall and gets into the bloodstream. It then breaks down and releases its active ingredients whereby they have a much better opportunity to reach their targeted cells and tissues.
Gamma aminobutyric acid (GABA) is a naturally occurring amino acid that works as a neurotransmitter in your brain. Neurotransmitters function as chemical messengers. GABA is considered an inhibitory neurotransmitter because it blocks, or inhibits, certain brain signals and decreases activity in your nervous system. When GABA attaches to a protein in your brain known as a GABA receptor, it produces a calming effect. This can help with feelings of anxiety, stress, and fear. It may also help to prevent seizures. As a result of these properties, GABA has also become a popular supplement in recent years. This is partly because it isn't available from many food sources. The only foods that contain GABA are fermented ones, such as kimchi, miso, and tempeh.
Melatonin is a hormone made in the body. It regulates night and day cycles or sleep-wake cycles. Melatonin in supplements is usually made in a lab.
Darkness triggers the body to make more melatonin, which signals the body to sleep. Light decreases melatonin production and signals the body to be awake. Some people who have trouble sleeping have low levels of melatonin. It's thought that adding melatonin from supplements might help them sleep.
Glutathione is a substance made from the amino acids glycine, cysteine, and glutamic acid. It is produced by the liver and involved in many body processes. Glutathione is involved in tissue building and repair, making chemicals and proteins needed in the body, and in immune system function.
Many factors are involved in how efficiently a supplement gets absorbed into the body where it is intended to go. Scientific research has shown that many tablet, capsule and liquid vitamins and supplements have an average bio-availability and absorption rate of only 5-20%. Liposomes are purported to increase the bioavailability and absorption rate by up to 80% in some cases.
Learn more about NuMedica's new line of advanced liposomal professional-grade supplements.
Nutrient absorption begins with digestion in the stomach. Our overall health is dependent upon the health of our immune system which resides primarily in our gut. Scientists are finding new ways to deliver the nutrients within a supplement to the targeted area of the body more efficiently. Nanotechnology appears to be a promising method to help you get the most out of your supplements, and possibly foods, which may help to improve your health.
Facilitator Libby Wright interviews Dr. Jamie Wright who discusses the role of sleep in weight loss with participants of the Your Best Weight online education program. Dr. Wright is a board certified physician with a Masters Degree in Metabolic and Nutritional Medicine. The webinar last for 29 minutes and addresses questions submitted by the program participants.
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03/24/21 12:50 PM CDT
NuMedica informed us that this manufactured lot of Liposomal Tranquinox had a pump stem on the inside of the bottle that was a bit too long so it sometimes gets too close to the bottom of the bottle. They recommend that you open the top of the bottle, pull the pump assembly out, and trim a very small bit of the pump stem at the bottom to shorten it. The issue has been reported and will be addressed in the next manufactured lot of product. Thank you for your feedback.
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FirstFitness Nutrition Reseller Order Policy Change Effective December 1, 2023
SupplementRelief.com has been an Authorized Reseller (Team Member) of FirstFitness Nutrition (FFN) since April of 2020, selling FFN products directly from our website to our customers, handling the payment processing, order fulfillment, and customer service.
Effective December 1, 2023 FirstFitness Nutrition REQUIRES ALL Authorized Resellers, who have formerly sold FFN products DIRECTLY from their OWN website, to refer the PRODUCT PURCHASE to the Reseller's FFN Team Member website.
You may continue placing orders on SupplementRelief.com through December 31, 2023 for the remaining products we have in stock.
SupplementRelief.com's FFN Team Member website is:
You may also place your order directly over the phone by calling either SupplementRelief.com at 888.424.0032 or FirstFitness Nutrition's Customer Support line at 800.621.4348. Please let them know that your FFN Team Member is SUPPLEMENTRELIEF.COM.
You may continue to use this website (supplementrelief.com) for FFN product descriptions and other Wellness content from our Blog, Education, or Recipes, but on December 1, 2023:
The "Add to Cart" button will change to a "Purchase on FFN Team Member Website" button, and your browser will automatically open a new page on our FFN Team Member Website to purchase the product. You can stay on the new site and shop for ALL other FirstFitness Nutrition products without returning to this website.
If you formerly had a LOGIN ACCOUNT on SupplementRelief.com, it WILL NOT WORK on the FFN Team Member website. You will be given an option to create a new account on the FFN Team Member Website. You WILL NOT NEED your SupplementRelief.com account on this website anymore, unless you want to see your Order History for orders you placed on SupplementRelief.com in the past.
How Does This Affect Future FFN Purchases?
This means that as of December 1, 2023:
You may purchase FFN products only from an FFN Team Member website.
ALL ORDERS will now be PROCESSED and SHIPPED directly by FirstFitness Nutrition. The company name on your credit card statement will no longer say SUPPLEMENTRELIEF but will now say FIRST FITNESS.
You may optionally create a new account on our FFN Team Member website, or you can shop as a Guest— both options work fine. Setting up a new account on the FFN website is recommended to make placing future orders easier, as FirstFitness will already have your information to process your order once you log on to our Team Member website.
FirstFitness Nutrition's Order Policy
Delivery using UPS in 3 - 5 Business Days
30-Day Money-Back Guarantee
Shipping Charge is a minimum of $10 or 8.5% of the retail price of products purchased.
Sales Tax is automatically calculated and is based upon the Shipping Address.
You will receive an Order Receipt confirmation email directly from FirstFitness Nutrition (no longer directly from SupplementRelief.com) as soon as you complete placing your order on our Team Member website.
You will receive an Order Shipment confirmation email directly from UPS (no longer directly from SupplementRelief.com) with the tracking number as soon as your order ships.
Every FirstFitness Nutrition order, from every FFN Team Member website, is subject to the exact same Order Policy. This means that shipping charges and sales taxes will be calculated the same way for every FFN product purchased from every FFN Team Member Website.
FirstFitness VIP Customer Rewards Program
FirstFitness Nutrition offers a Customer Loyalty VIP Rewards Program for savings whereby you can earn future discounts on product purchased.
This is a monthly autoship program (called a Smart Ship) where you choose the product(s) you want shipped to you each month. You can easily create and then log into your Customer VIP Rewards account anytime and change the products on your monthly auto-ship or pause/cancel it.
Receive 20% in VIP Reward Points redeemable for Free Products (4 points for every dollar spent - 400 points = $100) after three consecutive Smart Ships
Free shipping on a monthly Smart Ship order of $100 or more
SupplementRelief.com wants the transition to the FFN Team Member website for future orders to be a smooth process.
Faith Hoffman, our Customer Support Specialist, is happy to assist you. We appreciate your business and are prepared to answer questions and provide additional details on any or all of the above information, policies, products, costs, discount opportunities and programs, etc.
Please get in touch with Faith at your convenience:
Faith Hoffman has spent 23 years in business practices, research, and customer relations for brand products and national companies. Lengthy hospital stays for auto-immune disorders, including the onset of heart and liver disease, led her to research the benefits of quality all-natural supplements and the importance of living a healthy lifestyle.
She became a customer of SupplementRelief.com three years ago. Positive results from healthy lifestyle changes and using quality, targeted supplements compelled her to share and recommend SupplementRelief.com products to family, friends, and clients. Studying through her journey and having a passion for helping others, she joined SupplementRelief.com as a customer support specialist in 2023.
When Faith is not assisting SupplementRelief.com customers, she enjoys singing gospel music, volunteering, and spending time with her family and pets.
Faith can be reached by email at [email protected] or by phone or text at (225) 316-5716.
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* These statements have not been evaluated by the Food and Drug Administration. These products and services are not intended to diagnose, treat, cure, or prevent any disease.
* There is NO GUARANTEE OF SPECIFIC RESULTS for the products or services offered, and the RESULTS CAN VARY for each individual.
FirstFitness Nutrition and NuMedica may be promoted and sold on the internet ONLY by Authorized Resellers who have been approved by, and have registered their website domain with these companies. They strictly prohibit, and actively monitor, the UNAUTHORIZED SALE or RESALE of their products in ALL online public shopping portals including Amazon, eBay, and others and into other countries. All products purchased in SupplementRelief.com are for PERSONAL USE ONLY and CANNOT BE RESOLD to others. Please report violations of Reseller Policy directly to FirstFitness Nutrition at 800.621.4348 and to NuMedica at 800.869.8100.
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Shipping & Handling
A safe and accurate address for delivery must be provided at the time the order is placed. Once an order has shipped, SupplementRelief.com is NOT responsible for lost or stolen packages CONFIRMED BY THE CARRIER to be delivered to the address provided for the order.
Since COVID-19, and the ensuing economic challenges in the USA economy, we respectfully ask that you allow some additional time for delivery for the carriers (USPS, UPS, and FedEx). Most orders still arrive on time, or near on time, but some may run late. We make every effort to get your order packed and into the carriers hands the same day, or by the next business morning if your order came in later in the previous day after carrier pickup, but we have no control over any delays that may happen within the shipping carrier's delivery system. Please order earlier for the time being if you are time-sensitive.
Orders that contain only FirstFitness Nutrition products have a shipping fee automatically calculated based upon the actual shipping weight of the items purchased. The charge ranges from $4.95 to $14.95.
For orders with NuMedica products you may choose from the shipping options below on the Order Checkout form in the Shipping Information section on the first line that says Choose Shipping Method.
*International shipping costs may be higher depending upon package weight and destination. We will contact you for your approval of the additional amount if this occurs.
SupplementRelief.com may use the email or phone number provided on your Order to call or text you regarding Order Status or to inform you of changes to the Order Policy.
When your order ships we will send you a confirmation email with the delivery tracking information.
Shipping anything these days internationally is expensive. COVID resulted in more rigorous customs import processes, and now with much higher energy prices, international shipping rates are higher.
FedEx is the most reliable and faster carrier, at least for now, but they are expensive. Our FedEx international shipping fee is a minimum of $79.95. It usually makes more sense to get several months of supply (3 months or more) in one order to minimize the shipping expense per order over time. While the added weight of additional items may increase the base shipping price by a little (usually 10-25% depending upon total weight and destination), it is usually not by very much relative to shipping an additional small order later.
We also offer a lower-cost international shipping option using GlobalPost International for $39.95. So far, they have been reliable in getting packages correctly delivered but it takes 2 - 4 times as long to get the package delivered. Packages may take longer to process in the receiving country's customs process and status updates may not be reported as quickly. Please be patient if you choose this option to save money.
Some International orders may cost more to ship depending upon weight and location. If that happens we will contact you first and get your approval for any additional charge before proceeding. International orders may also be subject to additional customs fees and duties/taxes based upon the destination country's customs import laws and policies. These fees are NOT known or included on our order form and are typically charged and collected by the shipping carrier when they are delivering the product to it's final destination once the package has cleared the destination country's customs process. It is recommended that the buyer research custom import fees for the products/services they are importing beforehand to be aware of potential, additional fees.
Shipping Refrigerated Products
Our manufacturers formulate their probiotics to ensure their products retain viability until they reach the consumer. Probiotics that are recommended to be refrigerated remain so until the time of shipment, then shipped alongside an ice pack to ensure potency (Note: Ice pack will not arrive frozen, and product may not arrive cold). Orders placed on a Thursday-Sunday requiring cold shipping will not ship until the following Monday.
If your order has not been shipped yet, you can request a cancellation. Your original purchase amount will be refunded within three business days. If your order has already shipped, see Returns and Refunds.
Changes, Returns and Refunds
If you want to make a change to your order, please email usas soon as possible so we can make the change before your order ships. If your order has already shipped you may incur additional shipping charges for the second shipment and the return label for any products returned.
If we have made a mistake on your order, or the product arrives in a damaged or unusable condition, we will make every reasonable effort to right the situation quickly to your satisfaction.
We accept returns subject to when the return is requested and the condition the product is returned in. All returns must first be authorized by contacting us. In your request, please let us know why you are returning the item(s). We will respond promptly with authorization, the return address, and a return shipping label if appropriate.
If your order has already shipped you can return any un-opened products within 30 days of receiving your order for a 100% refund of the price paid for the product, less the actual shipping charges we incurred to get the product to you originally and then returned, less a $10 restocking fee. Un-opened means the protective seal on the bottle or container, or the shrink-wrap on the box or kit, has not been broken and the product has not otherwise been damaged in any way. You may use the original packaging for the return or acquire your own. We will provide the return shipping label. We DO NOT accept returns for NuMedica products once the protective product seal has been broken.
Upon receipt of returned product(s), we will refund your credit card within three business days for the product(s) returned.