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Methyltransferase complexed with DNA, molecular model

Methylation Support

Epigenetics is the study of the way your external environment can impact your genes.

These changes to your genes are reversible and don't change your DNA the way that genetic changes do. Instead, they change how your cells read your genes.

Read on to learn more about DNA methylation and methylation support.


Methylation is an example of epigenetics, and it was one of the earliest epigenetic modifications found in humans. DNA methylation plays an essential role in many common human diseases.

What is Methylation?

Simply put, methylation is a biochemical reaction that occurs in the body. It occurs when carbon and hydrogen atoms are transferred from one substance to another.

This is how your body regulates many of the processes it does daily, including:

  • DNA production
  • Detoxification 
  • Metabolism 
  • Production of neurotransmitters
  • Histamine production 
  • Eye health 
  • Liver health 
  • Reproductive system
  • Hormone balance

Your body needs methylation to keep all its processes running as they should. The process of methylation essentially keeps all the correct switches turned on or off in the body.

What is DNA Methylation?

DNA methylation occurs when a methyl group transfers onto your DNA. This process turns a gene on or off.  

The methyl groups tell your body when it should or shouldn't read specific genes. For example, your body prevents cancer by telling a tumour forming gene to stay switched off.

A recent study suggests that your methylated DNA reduces as you age. This may be why you are more susceptible to disease as you get older.

What Can You Do For Methylation Support?

One of the main contributing factors to your body's ability to methylate correctly is your diet.

Certain nutrients are crucial for methylation; these are:

  • Folate 
  • Vitamins B12 & B6
  • Methionine
  • Choline
  • Polyphenols

The presence of folate is particularly important to your ability to methylate; the body converts it to its active form 5-MTHF.

Many of the nutrients required for the methylation process come from vegetables, especially dark, leafy green vegetables such as kale, spinach and broccoli.

You'll find B vitamins in meat, dairy and seafood products. Taking supplements for B vitamins can help ensure you get healthy quantities (especially if you're vegetarian or vegan).  

Consuming excessive alcohol may contribute to poor methylation ability.

How To Find Out If You Have a Healthy Methylation Process

There are genetic tests available to help you find out about your body's methylation capabilities. Although the results of these tests can be complex to interpret, they can be invaluable to your ability for preventing future disease.

If you want to learn more about your methylation cycle, speak to your doctor.

Eat a Balanced Diet to Support Methylation

DNA methylation is still a relatively new concept. There aren't hundreds of human studies yet to conclusively prove that diet and lifestyle choices impact methylation. 

Eating a whole food diet rich in plant foods is your best pathway to good health and disease prevention. Here are some ideas for adding antioxidant foods to your diet.

Supplements for Methylation Support:  Found

Cognitein

NuMedica

60/120 Vegetable Capsules
NuMedica
NuMedica Cognitien 60 vegetable capsules professional dietary supplement NuMedica Cognitien 60 vegetable capsules professional dietary supplement

Cognitein
60/120 Vegetable Capsules

Cognitive Function and Healthy Brain Aging*

Cognitein is a unique combination of magnesium L-threonate, L-taurine and L-theanine designed to help support healthy cognitive function. *
Gluten Free  Vegetable Capsule  Vegetarian  New  
SKU: NM589, NM591 - UPC: 812527015890, 812527015913
Health Categories *

Retail Price: $47.50

shopping cart icon  Add to Cart

Cognitive Function and Healthy Brain Aging*

Cognitein is a unique combination of magnesium L-threonate, L-taurine and L-theanine designed to help support healthy cognitive function. *



Liposomal Hydroxy B12

NuMedica

60 Servings
NuMedica
NuMedica LIposomal Hydroxy B12 - 30 Servings professional-grade supplement NuMedica LIposomal Hydroxy B12 - 30 Servings professional-grade supplement

Enhanced Absorption Technologies *

Provides 1,0000 mcg of vitamin B12 in a slow-release, long-acting form that may help your body maintain more steady levels of B12.*
Gluten Free  Vegetarian  New  
SKU: NM544 - UPC: 812527015449
Health Categories *

Retail Price: $41.90

shopping cart icon  Add to Cart

Enhanced Absorption Technologies *

Provides 1,0000 mcg of vitamin B12 in a slow-release, long-acting form that may help your body maintain more steady levels of B12.*



Liposomal MethylSorb

NuMedica

60 Servings
NuMedica
NuMedica Liposomal MethylSorb - 30 ml professional-grade supplement NuMedica Liposomal MethylSorb - 30 ml professional-grade supplement

Advanced Nutrient Absorption Technology*

Provides folate and B vitamins using liposomes to support healthy homocysteine levels and optimal methylation.*
Activated B Vitamins  Gluten Free  Quatrefolic  Vegetarian  
SKU: NM122 - UPC: 812527015159
Health Categories *

Retail Price: $55.95

shopping cart icon  Add to Cart

Advanced Nutrient Absorption Technology*

Provides folate and B vitamins using liposomes to support healthy homocysteine levels and optimal methylation.*



Methyl B-12 HP

NuMedica

60 Servings
NuMedica
NuMedica Methyl B-12 Rx - 60 lozenge professional-grade dietary supplement NuMedica Methyl B-12 Rx - 60 lozenge professional-grade dietary supplement

Methyl B-12 HP
60 Servings

Supports Healthy Homocysteine Levels*

Lozenge form and powerful natural supplement that contains vitamin B-12, which supports cognitive function and nervous system health.*
Gluten Free  Vegetarian  Popular  
SKU: NM129 - UPC: 812527011298

Retail Price: $30.50

shopping cart icon  Add to Cart

Supports Healthy Homocysteine Levels*

Lozenge form and powerful natural supplement that contains vitamin B-12, which supports cognitive function and nervous system health.*



Methyl Folate

NuMedica

60/120 Vegetable Capsules
NuMedica
NuMedica Methyl Folate - 5-MTHF - 60c professional-grade supplement NuMedica Methyl Folate - 5-MTHF - 60c professional-grade supplement

Methyl Folate
60/120 Vegetable Capsules

Biologically Active Form of Folate (5-MTHF)*

Contains therapeutic levels of active folate to support cardiovascular system health and may help to prevent neural tube defects.*
Activated B Vitamins  Gluten Free  Quatrefolic  Vegetable Capsule  Vegetarian  
SKU: NM59, NM60 - UPC: 812527010598, 812527010604

Retail Price: $24.90

shopping cart icon  Add to Cart

Biologically Active Form of Folate (5-MTHF)*

Contains therapeutic levels of active folate to support cardiovascular system health and may help to prevent neural tube defects.*



Methyl Folate HP

NuMedica

60 Vegetable Capsules
NuMedica
NuMedica Methyl Folate HP - 60c professional-grade supplement NuMedica Methyl Folate HP - 60c professional-grade supplement

Methyl Folate HP
60 Vegetable Capsules

High-Potency, Biologically-Active Folate with 5,200 mcg per Capsule *

Contains high-potency, biologically-active folate to support cardiovascular system health and help to prevent neural tube defects.*
Gluten Free  Quatrefolic  Vegetable Capsule  Vegetarian  
SKU: NM967 - UPC: 812527010109

Retail Price: $55.95

shopping cart icon  Add to Cart

High-Potency, Biologically-Active Folate with 5,200 mcg per Capsule *

Contains high-potency, biologically-active folate to support cardiovascular system health and help to prevent neural tube defects.*



Methyl Folate Optimizer

NuMedica

60 Vegetable Capsules
NuMedica
NuMedica Methyl Folate Optimizer - 60 vegetable capsule professional-grade dietary supplement NuMedica Methyl Folate Optimizer - 60 vegetable capsule professional-grade dietary supplement

Methyl Folate Optimizer
60 Vegetable Capsules

Advanced Methylation Support*

Advanced methylation support with active folate to support cardiovascular system health and help to prevent neural tube defects.*
Activated B Vitamins  Gluten Free  Quatrefolic  Vegetable Capsule  Vegetarian  New  
SKU: NM305 - UPC: 812527010116

Retail Price: $44.95

shopping cart icon  Add to Cart

Advanced Methylation Support*

Advanced methylation support with active folate to support cardiovascular system health and help to prevent neural tube defects.*



Methyl-Plex B

NuMedica

60 Vegetable Capsules
NuMedica
NuMedica Methyl-Plex B - 60 vegetable capsule professional-grade dietary supplement NuMedica Methyl-Plex B - 60 vegetable capsule professional-grade dietary supplement

Methyl-Plex B
60 Vegetable Capsules

Comprehensive Methylation Support Formula*

Powerful supplement with therapeutic levels of B vitamins that support cardiovascular system health.*
Activated B Vitamins  Gluten Free  Quatrefolic  Vegetable Capsule  Vegetarian  
SKU: NM76 - UPC: 812527010765

Retail Price: $33.90

shopping cart icon  Add to Cart

Comprehensive Methylation Support Formula*

Powerful supplement with therapeutic levels of B vitamins that support cardiovascular system health.*


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