Supplements for Fatigue, Brain Fog, Memory, Sleep, ADHD & Behavioral Issues?

Editorial stewardship: SupplementRelief.com | Originally published: 01/18/18 | Last updated: 05/28/26

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Many people suffer from Neuro-Endocrine-Immune diseases and disorders. This is a very deep and very specific group of issues, and this article will only scratch the surface of what these products can do. I encourage you to dig deeper into product descriptions if something piques your interest.

Inflammation is at the Root of Neuro-Immune Diseases and Disorders

Many people look for medications to treat the symptoms, but what if, by using some simple nutritional supplements, you could work on issues like fatigue, cognitive issues, ADHD, and even Autism? What if you could reduce memory and sleep problems and improve behavioral issues so common with Neuro-Immune disease? It can work if you understand that the root cause, the common denominator to all of these issues, is inflammation!

Supplements for Neuro-Immune Support from NuMedica

Consider these NuMedica supplements specifically targeting Neuro-Immune health: Cognitive Balance, Methyl Folate, Mitochondrial Recharge, and Pathogen Defense. These supplements are meant to work in harmony for the best results. They can be used individually based on symptoms but usually work best in groups.

NuMedica Cognitive Balance 120c
NuMedica Methyl Folate 5-MTHF 60c/120c
NuMedica Mitochondrial Recharge 90c
NuMedica Pathogen Defense 120c

NuMedica Cognitive Balance

Cognitive Balance is a supplement that targets low dopamine production. Using a variety of vitamins and minerals, including activated vitamin Bs, boosts cognitive balance and vitamin levels in the nervous system, which boosts the body's natural ability to create dopamine. Dopamine is a chemical in the brain (neurotransmitter) that is responsible for seeking pleasure/reward and learning behaviors. When people suffer from low dopamine levels, it has been linked to issues such as:

  • Sleep disturbances
  • Motor skill issues
  • Poor memory
  • Concentration and Focus issues including ADHD
  • Mood disturbances
  • Learning disabilities
  • Chronic pain conditions like fibromyalgia and restless leg syndrome

Over 93% of Neuro-Immune issues are rooted in methylation issues, which then cause inflammation. Methylation is an extremely complex process, which I will not attempt to explain here. In our context, I am speaking of methylation as detoxifying the body. Research is beginning to show that some patients with Autism Spectrum Disorder have a defect in their Neuro-Methylation Process. In my very simple explanation, this means that they cannot detoxify their neurological pathways. This causes inflammation and, thus, brain health issues.

NuMedica Methyl Folate 5-MTHF

MethylFolate 5 (MTHF5) deals specifically with this methylation issue. It will help the person better methylate and detoxify their system. The cream is based in B Vitamins and works with the MethylFolate 5, both as the most bioavailable form available on the market.

NuMedica NuMedica Mitochondrial Recharge

Neuro-Immune issues often cause fatigue. That's where our next supplement can make a serious impact! Mitochondrial Recharge is a supplement that works to recharge your cells often depleted by, you guessed it, inflammation! Your Mitochondria are responsible for the power source for your cells (ATP), and if they become depleted, you can have a whole host of issues like:

  • Fatigue
  • Delayed Healing
  • Poor Muscle Tone/Weakness
  • Developmental Delays/Disabilities
  • Gastrointenstinal Disorders
  • Immune Weakness
  • Neurological Instability and sometimes even Seizures
  • Growth Delay

Bottom line with this supplement, if your mitochondria are weak, you're setting yourself up for trouble! Mitochondrial Recharge helps to support and restore your mitochondria!

NuMedica Pathogen Defense

Pathogen Defense is last, but certainly not least, in our lineup. It's a powerful supplement that works to help heal chronic infections and gut health issues. Gut inflammation and disease have been linked to:

  • Chronic Infections
  • History of Yeast
  • History of Bacterial or Fungal Infections
  • Gut Issues (Bowel Irritation, Constipation, Diarrhea)
  • Chronic Sinus Infections
  • Requiring Multiple Doses of Antibiotics to Heal

This broad spectrum supplement helps to combat the overgrowth of yeast, viral activity, and bacterial overgrowth and is a great weapon in the arsenal against chronic Neruo-Immune Disease.


As with all of our products, we recommend that you take this journey with your healthcare provider, but DO talk with them about alternatives or additions to drug therapy alone! This article is meant to educate you on options, but please remember that you are your best advocate, and only you can decide what is right for your situation!


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