Wheat Gluten, Inflammation & Chronic Disease

When Did Food Become Our Enemy?

    2016-02-0702/07/16   
Nutrition  

It could be that the primary key to health and wellbeing lay within our gastrointestinal tract. With obesity and childhood behavioral disorders at seemingly epidemic levels and our "healthcare" system lacking answers, where do we turn?

What is the common feature of all chronic disease?

Intuitively we know that this level of disease, dis-ease, and malaise is not normal, but we do not seem to know how to change our situation. I would like to offer some basic insights, supported by cutting edge science, that you can try in your life today to see if they can help you.

Inflammation is the common feature of all chronic disease.

What causes this inflammation?

The immune system.

What is driving the immune system to create inflammation?

Food... and other things. But I am going to focus on food, specifically wheat gluten, to illustrate the interaction between food, the immune system, genetics, and inflammation.

Gluten can effect different people in different ways depending on their underlying genetic predisposition, timing of exposure to gluten as a child, and the microbiological environment of the GI tract.

There are at least three distinct entities linked to gluten:

  • Celiac Disease, which is an autoimmune reaction caused by exposure to gluten
  • Gluten Sensitivity, encompassing people who have clinical symptoms when they ingest gluten but they do NOT have autoimmune tissue destruction
  • Potential Celiac Disease, whereby people are making antibodies to their own tissue as a result of gluten exposure, but they DO NOT yet have small bowel disease

70% of the immune system cells are located around the GI tract

There are two primary arms of the immune system: the innate arm which involves an immune cell "attacking" the foreign product with chemicals; and the acquired or "learned" arm, which produces anti-bodies that adhere to the foreign particle, attracting other inflammatory cells.

Celiac Disease

Celiac disease seems to primarily involve the acquired arm of the immune system. Nearly 100% of people with Celiac Disease have a genetic trait called HLA DQ2 or HLA DQ8; but, only about 4% of people with this genetic trait will develop Celiac Disease. Celiac Disease involves the development of antibodies to tissues, causing the immune system to damage the intestinal tissue.

Gluten Sensitivity

Gluten sensitivity can cause similar gastrointestinal reactions to gluten, but does not cause the autoimmune reaction of the acquired immune system. Instead, gluten activates the innate immune system, leading to an inflammatory cascade that can create far reaching symptoms. Interestingly, gluten sensitivity symptoms can manifest as psychiatric symptoms. In fact, non-celiac reactions to gluten have been linked to acute psychosis, schizophrenia, and other mental illness such as autism. Some authors disagree with this connection.

Gluten studies do help us understand one thing: the immune system can respond to food and create a wide range of disease and symptoms states which are often difficult for patients and clinicians to link to the ingested food(s).

Although it is clear from clinical studies that food allergy testing (IgG) is primarily an indication of exposure to food, not a reaction to food, it may be effective to look at how the body's innate immune system reacts to food. By understanding what foods activate the immune system, causing inflammation, we can reduce this stress burden on our system and observe for symptoms improvement.

Improving the course of neuro-immune diseases, autism, and autoimmune conditions requires patience and persistence- there is almost NEVER a silver bullet. Focused testing of the immune and hormone systems combined with nutritional and lifestyle changes can improve quality of life.


SupplementRelief provides NuMedica's complete line of supplements for Gluten Sensitivity.

Jamie Wright wellness expert
Author

Dr. Jamie Wright, DO, MS, FACOOG, ABAARM has over 20 years of experience in the medical field. He graduated from Michigan State University / College of Osteopathic Medicine medical school in 2001. He is Double Board Certified with a Master's Degree in Metabolic and Nutritional Medicine.

Learn more about Jamie Wright.

  Related Content

We encourage you to take advantage of these FREE Wellness Resources on our website.


modern grocery store with gluten free and dairy free foods on the outer isles

Help for Gluten-Free & Dairy-Free Living

Eliminating or minimizing Gluten and Dairy from your diet isn't necessary for everyone but some certainly benefit from making these lifestyle changes. Regardless, we all benefit from eating more natural, whole foods and less processed foods. Learn more about gluten-free and dairy-free nutrition options and take advantage of the educational resources, shopping list, and recipes.


large wooden Trojan Horse

Liposomes - A Trojan Horse for Supplement Effectivity?

Many factors are involved in how efficiently a supplement gets absorbed into the body where it is intended to go. Scientific research has shown that many tablet, capsule and liquid vitamins and supplements have an average bio-availability and absorption rate of only 5-20%. Liposomes are purported to increase the bioavailability and absorption rate by up to 80% in some cases.

Learn more about NuMedica's new line of advanced liposomal professional-grade supplements.


gluten free

So What's The Big Deal About Gluten?

Is Gluten Bad? Gluten just is. The problem is, it generally is not being used in the correct proportions any more. So let's take a moment to explore what gluten really is.


lower female abdomen depicting celiac disease

Understanding Celiac Disease and the Relationship to Gluten Sensitivity

Celiac disease occurs for some people who have a problem processing gluten, which is a protein found in many foods. The gluten triggers an immune response that is not normal and damages the inside of the small intestine. Once that happens it is difficult to absorb the nutrients needed from the foods eaten.


Illustration of inflammation in the gut for an obese woman.

Understanding Inflammation's Link to Obesity, Diabetes, & Disease

This article provides introductory knowledge on the role of blood sugar and body fat on inflammation. Inflammation is the center-point of disease and the main contributor to obesity.


webinar

Webinar: Four Letter Word for F.O.O.D.

Facilitator Libby Wright discusses the unhealthy types of food typically consumed in the S.A.D (Standard American Diet) with participants of the Your Best Weight online education program. She provides alternative food choices and recipes that are nutritious and taste great along with supplement recommendations including meal replacement protein shakes. The webinar last for 17 minutes and addresses questions submitted by the program participants.


Drawing of Boy In Bubble Protected by Immune System

Why You Should Care About Gut Health

The Gut (think intestinal/digestive tract) is where approximately 80% of your immune system lives. It's been overlooked in the general healthcare world, and here's why you should care about and for it.

  • Blog Post

    What is the common feature of all chronic disease?

    Intuitively we know that this level of disease, dis-ease, and malaise is not normal, but we do not seem to know how to change our situation. I would like to offer some basic insights, supported by cutting edge science, that you can try in your life today to see if they can help you.

    Inflammation is the common feature of all chronic disease.

    What causes this inflammation?

    The immune system.

    What is driving the immune system to create inflammation?

    Food... and other things. But I am going to focus on food, specifically wheat gluten, to illustrate the interaction between food, the immune system, genetics, and inflammation.

    Gluten can effect different people in different ways depending on their underlying genetic predisposition, timing of exposure to gluten as a child, and the microbiological environment of the GI tract.

    There are at least three distinct entities linked to gluten:

    • Celiac Disease, which is an autoimmune reaction caused by exposure to gluten
    • Gluten Sensitivity, encompassing people who have clinical symptoms when they ingest gluten but they do NOT have autoimmune tissue destruction
    • Potential Celiac Disease, whereby people are making antibodies to their own tissue as a result of gluten exposure, but they DO NOT yet have small bowel disease

    70% of the immune system cells are located around the GI tract

    There are two primary arms of the immune system: the innate arm which involves an immune cell "attacking" the foreign product with chemicals; and the acquired or "learned" arm, which produces anti-bodies that adhere to the foreign particle, attracting other inflammatory cells.

    Celiac Disease

    Celiac disease seems to primarily involve the acquired arm of the immune system. Nearly 100% of people with Celiac Disease have a genetic trait called HLA DQ2 or HLA DQ8; but, only about 4% of people with this genetic trait will develop Celiac Disease. Celiac Disease involves the development of antibodies to tissues, causing the immune system to damage the intestinal tissue.

    Gluten Sensitivity

    Gluten sensitivity can cause similar gastrointestinal reactions to gluten, but does not cause the autoimmune reaction of the acquired immune system. Instead, gluten activates the innate immune system, leading to an inflammatory cascade that can create far reaching symptoms. Interestingly, gluten sensitivity symptoms can manifest as psychiatric symptoms. In fact, non-celiac reactions to gluten have been linked to acute psychosis, schizophrenia, and other mental illness such as autism. Some authors disagree with this connection.

    Gluten studies do help us understand one thing: the immune system can respond to food and create a wide range of disease and symptoms states which are often difficult for patients and clinicians to link to the ingested food(s).

    Although it is clear from clinical studies that food allergy testing (IgG) is primarily an indication of exposure to food, not a reaction to food, it may be effective to look at how the body's innate immune system reacts to food. By understanding what foods activate the immune system, causing inflammation, we can reduce this stress burden on our system and observe for symptoms improvement.

    Improving the course of neuro-immune diseases, autism, and autoimmune conditions requires patience and persistence- there is almost NEVER a silver bullet. Focused testing of the immune and hormone systems combined with nutritional and lifestyle changes can improve quality of life.


    SupplementRelief provides NuMedica's complete line of supplements for Gluten Sensitivity.

    Jamie Wright wellness expert
    Author

    Dr. Jamie Wright, DO, MS, FACOOG, ABAARM has over 20 years of experience in the medical field. He graduated from Michigan State University / College of Osteopathic Medicine medical school in 2001. He is Double Board Certified with a Master's Degree in Metabolic and Nutritional Medicine.

    Learn more about Jamie Wright.

  • Related Content

      Related Content

    We encourage you to take advantage of these FREE Wellness Resources on our website.


    modern grocery store with gluten free and dairy free foods on the outer isles

    Help for Gluten-Free & Dairy-Free Living

    Eliminating or minimizing Gluten and Dairy from your diet isn't necessary for everyone but some certainly benefit from making these lifestyle changes. Regardless, we all benefit from eating more natural, whole foods and less processed foods. Learn more about gluten-free and dairy-free nutrition options and take advantage of the educational resources, shopping list, and recipes.


    large wooden Trojan Horse

    Liposomes - A Trojan Horse for Supplement Effectivity?

    Many factors are involved in how efficiently a supplement gets absorbed into the body where it is intended to go. Scientific research has shown that many tablet, capsule and liquid vitamins and supplements have an average bio-availability and absorption rate of only 5-20%. Liposomes are purported to increase the bioavailability and absorption rate by up to 80% in some cases.

    Learn more about NuMedica's new line of advanced liposomal professional-grade supplements.


    gluten free

    So What's The Big Deal About Gluten?

    Is Gluten Bad? Gluten just is. The problem is, it generally is not being used in the correct proportions any more. So let's take a moment to explore what gluten really is.


    lower female abdomen depicting celiac disease

    Understanding Celiac Disease and the Relationship to Gluten Sensitivity

    Celiac disease occurs for some people who have a problem processing gluten, which is a protein found in many foods. The gluten triggers an immune response that is not normal and damages the inside of the small intestine. Once that happens it is difficult to absorb the nutrients needed from the foods eaten.


    Illustration of inflammation in the gut for an obese woman.

    Understanding Inflammation's Link to Obesity, Diabetes, & Disease

    This article provides introductory knowledge on the role of blood sugar and body fat on inflammation. Inflammation is the center-point of disease and the main contributor to obesity.


    webinar

    Webinar: Four Letter Word for F.O.O.D.

    Facilitator Libby Wright discusses the unhealthy types of food typically consumed in the S.A.D (Standard American Diet) with participants of the Your Best Weight online education program. She provides alternative food choices and recipes that are nutritious and taste great along with supplement recommendations including meal replacement protein shakes. The webinar last for 17 minutes and addresses questions submitted by the program participants.


    Drawing of Boy In Bubble Protected by Immune System

    Why You Should Care About Gut Health

    The Gut (think intestinal/digestive tract) is where approximately 80% of your immune system lives. It's been overlooked in the general healthcare world, and here's why you should care about and for it.


The information, knowledge, and experience shared on this website is the opinion of SupplementRelief.com. This site and its content is intended to enhance your knowledge base as YOU MAKE YOUR OWN HEALTHCARE DECISIONS in partnership with your qualified health professional. These statements have not been evaluated by the Food and Drug Administration. Any products referred to are not intended to diagnose, treat, cure or prevent any disease.

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