The coordination of hypothalamic, pituitary, adrenal, circadian, and metabolic signaling that regulates cortisol dynamics and systemic adaptation to stress.
How stress hormones are coordinated with the body's daily rhythms and energy needs.
Includes integration of HPA-axis signaling with circadian timing, metabolic demands, and broader endocrine control. Distinct from Neuroendocrine Stress Regulation, which governs the stress response more directly, and from Hormonal Feedback Loop Stability, which governs correction and damping of endocrine signaling.
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